Men denied life-extending prostate cancer drug on NHS in England

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Hugh Pym and Ian Atkinson

BBC Information

Institute of Cancer Research Abiraterone tablets on a tableInstitute of Most cancers Analysis

Abiraterone tablets will help cease prostate most cancers spreading

A most cancers charity has stated it’s “indignant and pissed off” that ministers and well being officers haven’t accredited the supply of a life-extending prostate most cancers drug by way of the NHS in England.

The drug, abiraterone, has been accessible in Scotland and Wales for 2 years for high-risk sufferers whose most cancers has not but unfold, however not in England and Northern Eire.

In a letter to Prostate Most cancers UK, seen by the BBC, Well being Minister Karin Smyth stated the choice by NHS England, following a prolonged overview, was “primarily based on general affordability” and that “it could not be applicable to intervene”.

The federal government stated pressing recommendation had been requested on the problem.

The charity stated it was a “dire and pressing scenario in England” with “a bureaucratic blockage denying males this remedy”.

A Division of Well being and Social Care spokesperson stated: “We perceive the frustration and upset of some sufferers who can’t entry this probably life-saving remedy. Ministers have requested pressing recommendation on the problem.”

Though not a remedy, abiraterone will help cease prostate most cancers spreading to different elements of the physique.

In England and Northern Eire, the drug is simply accredited for males with very superior prostate most cancers which has unfold already.

In Wales and Scotland, folks with the illness that has not but unfold may get it.

Analysis has proven that for these earlier stage sufferers, the survival price after six years is improved and that the drug halved the speed of development of the most cancers.

Giles Turner Giles Turner, from Sussex, has paid privately to access abirateroneGiles Turner

The charity says many lives might be prolonged by the drug, given the findings from a trial referred to as Stampede, printed in 2022.

It discovered improved odds of survival amongst males given the drug alongside ordinary care, and concluded that abiraterone must be thought-about a brand new customary remedy.

In line with figures from NHS England, annually about 8,400 sufferers have high-risk prostate most cancers that has not but unfold.

Utilizing the Stampede assumptions, 672 of these males might die prematurely with out entry to abiraterone.

In October 2023, BBC Information spoke to Giles Turner, a retired banker residing in Sussex. He was recognized with prostate most cancers earlier that yr however was advised that abiraterone couldn’t be obtained on the NHS in England.

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He selected to pay for remedy with the drug at £250 a month. He advised us then that he felt “very lucky” to have the ability to afford it, however outraged for others who couldn’t.

On the time, NHS England stated it was reviewing the drug’s use for a wider vary of males.

Nonetheless, in December 2024 it advised Prostate Most cancers UK that “it has not been doable to establish the mandatory recurrent headroom in income budgets”.

As a result of abiraterone is a generic drug which has gone “off patent” and is licensed for just one group of prostate most cancers sufferers, there’s a sophisticated course of to get it accredited for wider use.

Every year, NHS England could make “discretionary” funding selections with a specialist advisory group, nevertheless it has chosen to not for this drug.

Smyth’s letter earlier this month stated the method had to take a look at “the general funds influence of introducing a brand new remedy primarily based on affected person volumes”, and ministers wouldn’t intervene.

Mr Turner stated he was “surprised” that almost one-and-a-half years after the BBC report, NHS England had not caught up with NHS Scotland and NHS Wales.

He has spent £20,000 to this point on his remedy, and stated he felt it was fallacious that whereas costly new patented medicine remedies might be funded, abiraterone – costing the NHS £77 per pack per 30 days – couldn’t be.

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